Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5806483 | 1.00 | KMT2A (0.67) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL13211186 | 0.89 | KMT2A (0.64) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL3016463 | 0.89 | KMT2A (0.64) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL16829044 | 0.84 | KMT2A (0.68) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL21048453 | 0.84 | KMT2A (0.68) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL8496628 | 0.82 | KMT2A (0.47) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL13299867 | 0.82 | KMT2A (0.47) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL13319545 | 0.78 | ALDH1A1 (0.62) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL19502792 | 0.77 | KMT2A (0.60) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL19502791 | 0.77 | KMT2A (0.60) | KMT2ATSHRHSD17B10ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030211-A2 | ACYCLIC SULPHONAMIDES | VERNALIS (R & D) LIMITED (GB) | 2006-03-23 | — | — | WO | disclosed |