Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515591 | 1.00 | HPGD (0.33) | HPGDSMN1; SMN2TP53MAPT | |
| SCHEMBL21067111 | 0.89 | CYP3A4 (0.32) | HPGDSMN1; SMN2TP53MAPT | |
| SCHEMBL30577084 | 0.89 | CYP3A4 (0.32) | HPGDSMN1; SMN2TP53MAPT | |
| SCHEMBL29878039 | 0.86 | — | — | |
| SCHEMBL2655737 | 0.86 | — | — | |
| SCHEMBL14120504 | 0.70 | APLNR (0.37) | HPGDMAPT | |
| SCHEMBL5796064 | 0.69 | — | — | |
| SCHEMBL6729838 | 0.67 | KDM4E (0.31) | HPGD | |
| SCHEMBL23063893 | 0.67 | — | — | |
| SCHEMBL28275 | 0.66 | LOXL2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111556871-B | 1H-pyrazolo [4,3-b ] pyridines as PDE1 inhibitors | H.隆德贝克有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-110099901-B | Pyrazolo [3,4-b ] pyridines and imidazo [1,5-b ] pyridazines as PDE1 inhibitors | H.隆德贝克有限公司 | 2023-01-03 | — | — | CN | disclosed |