Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.51 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30165068 | 0.84 | PARP1 (0.52) | TIPARPPARP1ALDH1A1MEN1KMT2A | |
| SCHEMBL24968384 | 0.82 | TIPARP (0.59) | TIPARPSLC6A7PARP1ALDH1A1LMNA | |
| SCHEMBL30165123 | 0.73 | SLC6A7 (0.60) | TIPARPSLC6A7ALDH1A1MEN1KMT2A | |
| SCHEMBL30715134 | 0.72 | SLC6A7 (0.55) | TIPARPSLC6A7ALDH1A1LMNAMEN1 | |
| SCHEMBL30390234 | 0.72 | TIPARP (0.60) | TIPARPSLC6A7ALDH1A1LMNAMEN1 | |
| SCHEMBL25272191 | 0.72 | TIPARP (0.60) | TIPARPSLC6A7ALDH1A1LMNAMEN1 | |
| SCHEMBL25336879 | 0.72 | TIPARP (0.68) | TIPARPSLC6A7PARP1ALDH1A1LMNA | |
| SCHEMBL30715195 | 0.71 | SLC6A7 (0.54) | TIPARPSLC6A7ALDH1A1LMNAMEN1 | |
| SCHEMBL25274054 | 0.71 | TIPARP (0.58) | TIPARPSLC6A7ALDH1A1LMNAMEN1 | |
| SCHEMBL30390275 | 0.71 | TIPARP (0.58) | TIPARPSLC6A7ALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |