SCHEMBL30165032 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	TIPARP	Q7Z3E1	17/20	0.45

▸	TRPV1	Q8NER1	1/20	0.40

▸	PARP1	P09874	1/20	0.40

▸	CYP2C9	P11712	1/20	0.40

▸	PARP14	Q460N5	1/20	0.40

▸	PARP16	Q8N5Y8	1/20	0.40

▸	PARP12	Q9H0J9	1/20	0.40

▸	TNKS2	Q9H2K2	1/20	0.40

▸	PARP11	Q9NR21	1/20	0.40

▸	PARP2	Q9UGN5	1/20	0.40

▸	PARP4	Q9UKK3	1/20	0.40

▸	PARP3	Q9Y6F1	1/20	0.40

▸	TRPA1	O75762	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24967951	1.00	TIPARP (0.45)	TIPARPTRPV1PARP1CYP2C9PARP14
SCHEMBL24968392	0.88	TIPARP (0.46)	TIPARPTRPV1TRPA1
SCHEMBL24967938	0.87	TRPA1 (0.54)	TIPARPTRPV1TRPA1
SCHEMBL30164987	0.87	TRPA1 (0.54)	TIPARPTRPV1TRPA1
SCHEMBL24968391	0.85	TIPARP (0.44)	TIPARPTRPV1TRPA1
SCHEMBL24967956	0.83	TIPARP (0.46)	TIPARPTRPV1TRPA1
SCHEMBL24968374	0.82	TIPARP (0.44)	TIPARPTRPV1PARP1TRPA1
SCHEMBL24968398	0.80	TIPARP (0.46)	TIPARPTRPV1PARP1
SCHEMBL24968229	0.74	TIPARP (0.52)	TIPARPPARP1CYP2C9PARP14PARP16
SCHEMBL24968175	0.74	TIPARP (0.49)	TIPARPPARP1CYP2C9PARP14PARP16

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023006013-A1	NOVEL PARP7 INHIBITOR AND USE THEREOF	上海齐鲁制药研究中心有限公司	2023-02-02	—	—	WO	disclosed