Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.54 |
| ▸ | TIPARP | Q7Z3E1 | 10/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24967938 | 1.00 | TRPA1 (0.54) | TRPA1TIPARPTRPV1SLC6A7KDM4E | |
| SCHEMBL24968392 | 0.89 | TIPARP (0.46) | TRPA1TIPARPTRPV1 | |
| SCHEMBL24967956 | 0.87 | TIPARP (0.46) | TRPA1TIPARPTRPV1 | |
| SCHEMBL30165032 | 0.87 | TIPARP (0.45) | TRPA1TIPARPTRPV1 | |
| SCHEMBL24967951 | 0.87 | TIPARP (0.45) | TRPA1TIPARPTRPV1 | |
| SCHEMBL24968374 | 0.86 | TIPARP (0.44) | TRPA1TIPARPTRPV1 | |
| SCHEMBL24967944 | 0.86 | CHRM2 (0.43) | TRPA1TIPARP | |
| SCHEMBL24967945 | 0.86 | CHRM2 (0.43) | TRPA1TIPARP | |
| SCHEMBL24968391 | 0.85 | TIPARP (0.44) | TRPA1TIPARPTRPV1HPGDSMN1; SMN2 | |
| SCHEMBL24968206 | 0.85 | TRPA1 (0.42) | TRPA1TIPARPTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |