Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TIPARP | Q7Z3E1 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24967932 | 1.00 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL24967933 | 0.82 | TIPARP (0.54) | TIPARPMEN1KMT2ANPSR1CYP1A2 | |
| SCHEMBL30851237 | 0.78 | NR1H2 (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL24967930 | 0.78 | NR1H2 (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL24968870 | 0.78 | TIPARP (0.57) | TIPARPCYP2C9POLB | |
| SCHEMBL24967931 | 0.77 | SYK (0.55) | PIK3CDPIK3CAPIK3CBPIK3CGKCNH2 | |
| SCHEMBL27233708 | 0.77 | TIPARP (0.51) | TIPARPNPSR1CYP2C9 | |
| SCHEMBL24968920 | 0.74 | MEN1 (0.46) | KCNH2TIPARPMEN1KMT2ANPSR1 | |
| SCHEMBL24968407 | 0.73 | CHRM2 (0.50) | TIPARPSMN1; SMN2LMNAHTT | |
| SCHEMBL30165090 | 0.73 | CHRM2 (0.50) | TIPARPSMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |