Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 9/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.48 |
| ▸ | SYK | P43405 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 4/20 | 0.47 |
| ▸ | RXRB | P28702 | 3/20 | 0.47 |
| ▸ | RXRG | P48443 | 3/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24967930 | 1.00 | NR1H2 (0.48) | NR1H2NR1H3SYKRXRARXRB | |
| SCHEMBL24967931 | 0.90 | SYK (0.55) | NR1H2NR1H3SYKPIK3CDPIK3CG | |
| SCHEMBL24967935 | 0.81 | SMN1; SMN2 (0.47) | RXRARXRBRXRGSMN1; SMN2CYP11B1 | |
| SCHEMBL30851253 | 0.81 | SMN1; SMN2 (0.47) | RXRARXRBRXRGSMN1; SMN2CYP11B1 | |
| SCHEMBL24967940 | 0.79 | HSD17B1 (0.52) | SYKPIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL30851292 | 0.79 | HSD17B1 (0.52) | SYKPIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL24967932 | 0.78 | PIK3CD (0.48) | SYKPIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL30165044 | 0.78 | PIK3CD (0.48) | SYKPIK3CDPIK3CGPIK3CAPIK3CB | |
| SCHEMBL27233839 | 0.72 | RXRA (0.48) | NR1H2NR1H3RXRARXRBRXRG | |
| SCHEMBL4207967 | 0.71 | PTGS1 (0.59) | PPARDCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642393-A | Novel PARP7 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2024-03-01 | — | — | CN | disclosed |