Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 9/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 3/20 | 0.36 |
| ▸ | KDM4B | O94953 | 3/20 | 0.36 |
| ▸ | KDM5C | P41229 | 3/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968853 | 0.83 | TIPARP (0.41) | TIPARP | |
| SCHEMBL24968854 | 0.82 | TIPARP (0.42) | TIPARP | |
| SCHEMBL24967955 | 0.78 | TIPARP (0.42) | TIPARP | |
| SCHEMBL24967973 | 0.72 | TIPARP (0.40) | TIPARP | |
| SCHEMBL24967972 | 0.72 | TIPARP (0.40) | TIPARP | |
| SCHEMBL24967921 | 0.72 | TIPARP (0.46) | TIPARP | |
| SCHEMBL24968242 | 0.72 | CHRM1 (0.39) | — | |
| SCHEMBL29165976 | 0.72 | SLC6A9 (0.38) | TIPARP | |
| SCHEMBL24968367 | 0.71 | TIPARP (0.49) | TIPARP | |
| SCHEMBL24968189 | 0.71 | TIPARP (0.65) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |