SCHEMBL30165136

SCHEMBL30165136

COc1ccc2ccc3ccccc3c2c1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.60
HPGD P15428 4/20 0.51
KDM4E B2RXH2 4/20 0.51
NQO1 P15559 1/20 0.48
ABCG2 Q9UNQ0 3/20 0.48
NPC1 O15118 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
RAB9A P51151 1/20 0.47
ALDH1A1 P00352 3/20 0.46
MAPK1 P28482 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MC4R P32245 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
NISCH Q9Y2I1 1/20 0.43
IDO1 P14902 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278576 0.86 MAPT (0.67) MAPTHPGDKDM4ENQO1NPC1
SCHEMBL30380487 0.86 MAPT (0.67) MAPTHPGDKDM4ENQO1NPC1
Ammonia Solution, Strong SCHEMBL11476305 0.84 MAPT (0.64) MAPTHPGDKDM4ENQO1NPC1
SCHEMBL15476789 0.84 NQO1 (0.58) MAPTHPGDKDM4ENQO1NPC1
SCHEMBL13744500 0.81 SMN1; SMN2 (0.58) MAPTHPGDKDM4ENQO1ABCG2
SCHEMBL15476760 0.81 MAPT (0.60) MAPTHPGDKDM4ENQO1ABCG2
SCHEMBL31340100 0.81 MAPT (0.60) MAPTHPGDKDM4ENQO1ABCG2
Cyanide SCHEMBL29227829 0.81 MAPT (0.60) MAPTHPGDKDM4ENQO1ABCG2
Formaldehyde SCHEMBL28780252 0.81 MAPT (0.60) MAPTHPGDKDM4ENQO1ABCG2
SCHEMBL20435263 0.80 MAPT (0.59) MAPTHPGDKDM4ENQO1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115745805-A Synthetic method of phenanthrene and naphthocycloheptene compounds 南通大学 2023-03-07 CN disclosed