SCHEMBL31340100

SCHEMBL31340100

COc1ccc2c(ccc3c4ccccc4ccc23)c1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.60
HPRT1 P00492 1/20 0.54
ALDH1A1 P00352 3/20 0.52
KDM4E B2RXH2 2/20 0.52
MAPK1 P28482 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NQO1 P15559 1/20 0.48
HPGD P15428 1/20 0.47
IDO1 P14902 1/20 0.46
TDO2 P48775 1/20 0.46
CYP2A6 P11509 1/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ABCB1 P08183 1/20 0.45
ABCC1 P33527 1/20 0.45
ABCG2 Q9UNQ0 1/20 0.45
MAOA P21397 1/20 0.44
CYP1A1 P04798 2/20 0.43
CYP1B1 Q16678 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15476760 1.00 MAPT (0.60) MAPTHPRT1ALDH1A1KDM4EMAPK1
SCHEMBL278576 0.90 MAPT (0.67) MAPTALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL30380487 0.90 MAPT (0.67) MAPTALDH1A1KDM4EMAPK1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL11476305 0.88 MAPT (0.64) MAPTALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL9765549 0.86 MAOA (0.54) MAPTALDH1A1KDM4EMAPK1SMN1; SMN2
Formaldehyde SCHEMBL28780252 0.85 MAPT (0.60) MAPTALDH1A1KDM4EMAPK1SMN1; SMN2
Cyanide SCHEMBL29227829 0.85 MAPT (0.60) MAPTALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL16641096 0.83 ALDH1A1 (0.50) MAPTALDH1A1KDM4EMAPK1SMN1; SMN2
SCHEMBL11505219 0.82 HTT (0.48) MAPTHPRT1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL27873366 0.81 MAPT (0.52) MAPTHPRT1ALDH1A1KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042726-A1 ENCODED DESIGN INTEGRATED SYNTHESIS OF NUCLEIC ACIDS, AND PHOSPHOLIPIDS, AND RELATED PHARMACEUTICAL PRODUCTS SCHAPER CHARLES (US) 2026-02-12 US disclosed
US-12473247-B2 Encoded design integrated synthesis of nucleic acids, and phospholipids, and related pharmaceutical products Schaper, Charles (US) 2025-11-18 US disclosed
US-20250074853-A1 ENCODED DESIGN INTEGRATED SYNTHESIS OF NUCLEIC ACIDS, AND PHOSPHOLIPIDS, AND RELATED PHARMACEUTICAL PRODUCTS SCHAPER CHARLES (US) 2025-03-06 US disclosed
US-12195423-B1 Encoded design integrated synthesis of nucleic acids, and phospholipids, and related pharmaceutical products SCHAPER CHARLES (US) 2025-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12195423-B1 Encoded design integrated synthesis of nucleic acids, and phospholipids, and related pharmaceutical products POLRMT, TARBP1, PHOSPHO1 MAPT 3753/4885HPRT1 478/4885ALDH1A1 4705/4885
US-20250074853-A1 ENCODED DESIGN INTEGRATED SYNTHESIS OF NUCLEIC ACIDS, AND PHOSPHOLIPIDS, AND RELATED PHARMACEUTICAL PRODUCTS POLRMT, TARBP1, PHOSPHO1 MAPT 3753/4885HPRT1 478/4885ALDH1A1 4705/4885
US-12473247-B2 Encoded design integrated synthesis of nucleic acids, and phospholipids, and related pharmaceutical products POLRMT, TARBP1, PHOSPHO1 MAPT 3753/4885HPRT1 478/4885ALDH1A1 4705/4885
US-20260042726-A1 ENCODED DESIGN INTEGRATED SYNTHESIS OF NUCLEIC ACIDS, AND PHOSPHOLIPIDS, AND RELATED PHARMACEUTICAL PRODUCTS POLRMT, POLM, PHOSPHO1 MAPT 4593/4885HPRT1 1907/4885ALDH1A1 3743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.