SCHEMBL278576

SCHEMBL278576

COc1ccc2ccccc2c1OC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.67
NQO1 P15559 1/20 0.54
ALDH1A1 P00352 4/20 0.52
KDM4E B2RXH2 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MAPK1 P28482 1/20 0.52
HPGD P15428 3/20 0.51
IDO1 P14902 2/20 0.50
TDO2 P48775 1/20 0.50
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
POLB P06746 2/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NISCH Q9Y2I1 1/20 0.46
CYP2A6 P11509 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30380487 1.00 MAPT (0.67) MAPTNQO1ALDH1A1KDM4ESMN1; SMN2
Ammonia Solution, Strong SCHEMBL11476305 0.98 MAPT (0.64) MAPTNQO1ALDH1A1KDM4ESMN1; SMN2
Formaldehyde SCHEMBL28780252 0.94 MAPT (0.60) MAPTNQO1ALDH1A1KDM4ESMN1; SMN2
Cyanide SCHEMBL29227829 0.94 MAPT (0.60) MAPTNQO1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL15476760 0.90 MAPT (0.60) MAPTNQO1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL31340100 0.90 MAPT (0.60) MAPTNQO1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL25986546 0.89 MAPT (0.64) MAPTNQO1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL30165136 0.86 MAPT (0.60) MAPTNQO1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL9765549 0.84 MAOA (0.54) MAPTNQO1ALDH1A1KDM4ESMN1; SMN2
SCHEMBL19894095 0.83 MAPT (0.61) MAPTNQO1ALDH1A1KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041669-A Epoxy resin monomer and preparation method and application thereof 中国建筑材料科学研究总院有限公司 2023-05-02 CN claimed
CN-110240586-A The preparation method of 2,3- dihydro -1H- benzo [f] chroman -2- amine derivative 山东百极地长制药有限公司 2019-09-17 CN claimed
CN-108530242-A A kind of direct nitration method of electron rich aromatic hydrocarbons 中国科学院青岛生物能源与过程研究所 2018-09-14 CN claimed
CN-108238878-A The synthetic method of 1,2- naphthoquinones organic intermediates 成都奥卡特科技有限公司 2018-07-03 CN claimed
CN-108069845-A An a kind of one step preparation method of bromo 1,4- naphthoquinones 大连理工大学 2018-05-25 CN claimed
CN-105085747-B Catalytic component and its catalyst for propylene polymerization 中国石油化工股份有限公司 2017-09-29 CN claimed
EP-2257515-B1 1,4-NAPHTHOQUINONE DERIVATIVES AND THERAPEUTIC USE THEREOF CENTRE NAT RECH SCIENT (FR) 2017-05-17 EP claimed
CN-104193609-B 1, 4-naphthoquinone derivatives and therapeutic uses thereof 国家科研中心 2017-04-12 CN claimed
CN-104357045-B There is synthetic method and the application thereof of the spiro-pyrans small-molecule fluorescent probe of extremely acid/pole alkali switching response BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) 2016-06-01 CN claimed
CN-103880621-B The method of reducing of preparation 7-methoxy-2-tetralone Nantong Baisheng Chemical Co., Ltd. (CN) 2015-08-12 CN claimed
CN-101468946-A Preparation technique of 5-methoxy-2-tetralone NANTONG LAIJIALI CHEMICAL CO L (CN) 2009-07-01 CN claimed
CN-101468943-A Preparation technique of 1,6-dimethoxynaphthalene NANTONG LAIJIALI CHEMICAL CO L (CN) 2009-07-01 CN claimed
CN-101434697-A Side chain type sulphonation polyarylether ketone based on naphthalene ring and preparation thereof UNIV JILIN (CN) 2009-05-20 CN claimed
CN-101434696-A Polyaromatic ether ketone containing diphenol naphthalin group and preparation thereof UNIV JILIN (CN) 2009-05-20 CN claimed
CN-101219941-A Naphthalenediol monomer containing symmetrical substituent, manufacturing method and application thereof UNIV JILIN (CN) 2008-07-16 CN claimed
CN-1965427-A Redox pairs for rechargeable lithium-ion batteries 3M INNOVATIVE PROPERTIES CO (US) 2007-05-16 CN claimed
CN-1724498-A Production method of 2,6-dimethoxynaphthalene NANTONG LAIJIALI CHEMICAL INDU (CN) 2006-01-25 CN claimed
CN-1226266-C 7-methoxy-2-telralin-one production method LAIJIALI CHEMICAL CO LTD NANTO (CN) 2005-11-09 CN claimed
CN-1438210-A 7-methoxy-2-telralin-one production method LAIJIALI CHEMICAL CO LTD NANTO (CN) 2003-08-27 CN claimed
CN-1265645-A Urokinase inhibitors ABBOTT LAB (US) 2000-09-06 CN claimed