Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200911 | 0.78 | NPC1 (0.41) | SMN1; SMN2DGAT1NPC1EGFRIGF1R | |
| SCHEMBL30719394 | 0.76 | DGAT1 (0.36) | DGAT1NPC1EGFRIGF1RSRC | |
| SCHEMBL22075678 | 0.75 | CYP11B1 (0.43) | ALDH1A1SMN1; SMN2DGAT1MAPTMAPK14 | |
| SCHEMBL16679708 | 0.74 | DGAT1 (0.43) | DGAT1NPC1EGFRIGF1RSRC | |
| SCHEMBL28966690 | 0.73 | DGAT1 (0.35) | DGAT1NPC1EGFRIGF1RSRC | |
| SCHEMBL30846745 | 0.73 | DUT (0.35) | DGAT1NPC1EGFRIGF1RSRC | |
| SCHEMBL1858220 | 0.72 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL1978323 | 0.72 | TYR (0.42) | DGAT1NPC1EGFRIGF1RSRC | |
| SCHEMBL24766780 | 0.71 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL1396124 | 0.71 | DGAT1 (0.37) | DGAT1NPC1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745971-B | PARP7 inhibitor and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-115745971-A | PARP7 inhibitor and application thereof | 重庆华森制药股份有限公司 | 2023-03-07 | — | — | CN | disclosed |