Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23884267 | 1.00 | KMT2A (0.46) | KMT2AMEN1ATMRAB9APOLB | |
| SCHEMBL23917009 | 0.84 | PIK3C3 (0.34) | KMT2AMEN1ATMRAB9APOLB | |
| SCHEMBL23917151 | 0.82 | RAB9A (0.45) | KMT2AMEN1ATMRAB9APOLB | |
| SCHEMBL23917150 | 0.81 | RAB9A (0.44) | KMT2AMEN1ATMRAB9APOLB | |
| SCHEMBL23884376 | 0.74 | ALDH1A1 (0.46) | KMT2AMEN1ATMRAB9APOLB | |
| SCHEMBL30165247 | 0.73 | PIK3C3 (0.43) | KMT2AMEN1RAB9APOLBEPHX2 | |
| SCHEMBL1623258 | 0.68 | EPHX2 (0.61) | KMT2AMEN1RAB9APOLBEPHX2 | |
| SCHEMBL23916972 | 0.67 | ALDH1A1 (0.43) | KMT2AMEN1POLBALDH1A1TSHR | |
| SCHEMBL3455269 | 0.67 | MEN1 (0.64) | KMT2AMEN1EPHX2CNR2FAAH | |
| SCHEMBL26551523 | 0.67 | TLR8 (0.44) | KMT2AMEN1ALDH1A1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916175-A | Novel 2-pyrimidinone analogs as potent antiviral agents against alphaviruses | 南方研究院 | 2023-04-04 | — | — | CN | disclosed |
| EP-4125845-A1 | NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES | Southern Research Institute (US) | 2023-02-08 | — | — | EP | disclosed |