Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30165226 | 0.89 | ALDH1A1 (0.35) | ALDH1A1EPHX1NPC1KMT2AMEN1 | |
| SCHEMBL29686867 | 0.87 | ADORA3 (0.38) | PTGESALOX5ALDH1A1EPHX1NPC1 | |
| SCHEMBL30165214 | 0.86 | ADORA3 (0.31) | ALDH1A1EPHX1NPC1P2RX7ADORA3 | |
| SCHEMBL30165343 | 0.86 | ADORA3 (0.37) | ALDH1A1EPHX1NPC1KMT2AMEN1 | |
| SCHEMBL30165322 | 0.86 | EPHX1 (0.30) | ALDH1A1EPHX1NPC1 | |
| SCHEMBL30165337 | 0.84 | — | — | |
| SCHEMBL30165265 | 0.84 | ALDH1A1 (0.32) | ALDH1A1EPHX1NPC1KMT2AMEN1 | |
| SCHEMBL30165275 | 0.84 | — | — | |
| SCHEMBL30165280 | 0.83 | ADORA3 (0.38) | PTGESALOX5KMT2AMEN1TP53 | |
| SCHEMBL30165308 | 0.83 | EPHX1 (0.31) | ALDH1A1EPHX1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125845-A1 | NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES | Southern Research Institute (US) | 2023-02-08 | — | — | EP | disclosed |