SCHEMBL30165657

SCHEMBL30165657

O=C(O)/C=C/C1C=CC=C(O)C1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7102475 0.77 TSHR (0.30) TSHRMAPK1HSD17B10TDP1
SCHEMBL1331671 0.77 TSHR (0.30) TSHRMAPK1HSD17B10TDP1
SCHEMBL6660448 0.77 TSHR (0.33) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL967282 0.71
SCHEMBL22753318 0.68 POLB (0.31) TSHR
SCHEMBL30932999 0.66 ALDH1A1 (0.33) HSD17B10THRB
SCHEMBL22207958 0.65 ALDH1A1 (0.33) THRB
SCHEMBL22207941 0.65 ALDH1A1 (0.33) THRB
SCHEMBL31437614 0.64
SCHEMBL10335366 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110698328-B Method for using dihydroresveratrol or stilbene derivatives and/or chemical variants thereof as antimicrobial agents 香港浸会大学 2022-12-20 CN disclosed