Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331671 | 0.72 | TSHR (0.30) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL7102475 | 0.72 | TSHR (0.30) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL967282 | 0.64 | — | — | |
| SCHEMBL24988792 | 0.58 | — | — | |
| SCHEMBL31437614 | 0.57 | — | — | |
| SCHEMBL6652488 | 0.57 | TSHR (0.40) | TSHRHSD17B10TDP1 | |
| Benzylamine SCHEMBL8533927 | 0.56 | LOXL2 (0.64) | TSHRKDM4ESMN1; SMN2 | |
| Benzylamine SCHEMBL10445229 | 0.56 | LOXL2 (0.64) | TSHRKDM4ESMN1; SMN2 | |
| Benzylamine SCHEMBL8533923 | 0.56 | LOXL2 (0.64) | TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL24435441 | 0.53 | HCAR2 (0.38) | TSHRMAPK1HSD17B10TDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401434-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | ELI LILLY AND COMPANY (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100403-A1 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPAR) | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |