Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.54 |
| ▸ | LCK | P06239 | 18/20 | 0.54 |
| ▸ | BTK | Q06187 | 4/20 | 0.54 |
| ▸ | EGFR | P00533 | 10/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30165801 | 1.00 | JAK3 (0.54) | JAK3LCKBTKEGFR | |
| SCHEMBL30160681 | 0.85 | JAK3 (0.52) | JAK3LCKBTKEGFR | |
| SCHEMBL30160759 | 0.85 | JAK3 (0.52) | JAK3LCKBTKEGFR | |
| SCHEMBL30165820 | 0.84 | JAK3 (0.50) | JAK3LCKBTKEGFR | |
| SCHEMBL30160897 | 0.81 | JAK3 (0.48) | JAK3LCKBTKEGFR | |
| SCHEMBL29931205 | 0.80 | JAK3 (0.59) | JAK3LCKBTKEGFR | |
| SCHEMBL28647032 | 0.80 | JAK3 (0.59) | JAK3LCKBTKEGFR | |
| SCHEMBL16798613 | 0.78 | JAK3 (0.55) | JAK3LCKBTKEGFR | |
| SCHEMBL21946880 | 0.78 | JAK3 (0.70) | JAK3LCKBTKEGFR | |
| SCHEMBL25598953 | 0.78 | JAK3 (0.70) | JAK3LCKBTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557933-B | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-115557933-A | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-01-03 | — | — | CN | disclosed |