Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026728 | 0.77 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9ANPSR1 | |
| SCHEMBL30165811 | 0.74 | SMN1; SMN2 (0.37) | MEN1KMT2ANPSR1ALDH1A1HSD17B10 | |
| SCHEMBL4515174 | 0.73 | KMT2A (0.58) | MEN1KMT2ANPC1RAB9ADRD2 | |
| SCHEMBL8686095 | 0.72 | S1PR1 (0.60) | MEN1KMT2ANPC1RAB9AGRM2 | |
| SCHEMBL8411315 | 0.72 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9ADRD2 | |
| SCHEMBL28986569 | 0.72 | SMN1; SMN2 (0.35) | MEN1KMT2ANPSR1S1PR1ALDH1A1 | |
| SCHEMBL11036674 | 0.71 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9ADRD2 | |
| SCHEMBL10887685 | 0.70 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9ADRD2 | |
| SCHEMBL11668124 | 0.70 | DRD2 (0.49) | MEN1KMT2ANPSR1DRD2ALDH1A1 | |
| SCHEMBL610584 | 0.69 | NPC1 (1.00) | MEN1KMT2ANPC1RAB9ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557933-A | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-01-03 | — | — | CN | disclosed |