Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25274502 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1L3MBTL1KMT2AMAPT | |
| SCHEMBL24054157 | 0.81 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1L3MBTL1KMT2AMAPT | |
| SCHEMBL24053480 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1L3MBTL1KMT2AMAPT | |
| SCHEMBL24053339 | 0.76 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1L3MBTL1KMT2AMAPT | |
| SCHEMBL17112092 | 0.76 | CSNK1A1 (0.46) | SMN1; SMN2ALDH1A1L3MBTL1KMT2AMAPT | |
| SCHEMBL24047399 | 0.75 | MAPT (0.43) | MAPTFFAR1PIN1 | |
| SCHEMBL30107573 | 0.75 | MAPT (0.43) | MAPTFFAR1PIN1 | |
| SCHEMBL3442581 | 0.69 | GRM5 (0.43) | ALDH1A1MAPTGAAFFAR1 | |
| SCHEMBL1186659 | 0.69 | — | — | |
| SCHEMBL24915617 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697991-B | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-115697991-A | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2023-02-03 | — | — | CN | disclosed |