Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.39 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25234865 | 1.00 | NOTUM (0.40) | NOTUMRPS6KA5RPS6KA4LMNAIDH1 | |
| SCHEMBL17601113 | 0.75 | IDH1 (0.43) | NOTUMRPS6KA5LMNAIDH1MAPT | |
| SCHEMBL25695365 | 0.74 | RPS6KA5 (0.40) | RPS6KA5RPS6KA4PANK3MAPTALDH1A1 | |
| SCHEMBL28760046 | 0.71 | KDM4E (0.50) | RPS6KA5RPS6KA4LMNAPANK3MAPT | |
| SCHEMBL11178856 | 0.69 | HTT (0.65) | LMNAMAPTHTTTP53NPSR1 | |
| SCHEMBL17601535 | 0.67 | RPS6KA5 (0.46) | RPS6KA5RPS6KA4PANK3MAPTALDH1A1 | |
| SCHEMBL24240345 | 0.66 | LMNA (0.62) | NOTUMLMNAMAPTALDH1A1HTT | |
| SCHEMBL7593026 | 0.64 | ALDH1A1 (0.60) | RPS6KA5RPS6KA4LMNAMAPTALDH1A1 | |
| SCHEMBL31205795 | 0.64 | NPSR1 (0.45) | RPS6KA5RPS6KA4PANK3MAPTALDH1A1 | |
| SCHEMBL5542210 | 0.64 | KCNN4 (0.55) | NOTUMALDH1A1L3MBTL1TSHRP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697991-B | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-115697991-A | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2023-02-03 | — | — | CN | disclosed |