Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.48 |
| ▸ | CDH1 | P12830 | 1/20 | 0.46 |
| ▸ | APC | P25054 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9928725 | 1.00 | TDP1 (0.49) | TDP1HSP90AA1ESR2CHEK2CDH1 | |
| SCHEMBL4076911 | 0.86 | TDP1 (0.66) | TDP1HSP90AA1ESR2CHEK2SMN1; SMN2 | |
| SCHEMBL9304008 | 0.85 | CHEK2 (0.49) | CHEK2THRBMEN1KMT2A | |
| SCHEMBL828113 | 0.82 | KDM4E (0.56) | TDP1HSP90AA1ESR2CHEK2SIRT2 | |
| SCHEMBL12004550 | 0.82 | KDM4E (0.49) | TDP1HSP90AA1ESR2CHEK2CDH1 | |
| SCHEMBL1193316 | 0.81 | RHEB (0.54) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1106071 | 0.79 | TDP1 (0.76) | TDP1HSP90AA1ESR2SIRT2SIRT1 | |
| SCHEMBL766092 | 0.79 | TDP1 (0.49) | TDP1HSP90AA1ESR2CHEK2SIRT2 | |
| SCHEMBL1870891 | 0.79 | FABP6 (0.55) | TDP1HSP90AA1ESR2SIRT2SIRT1 | |
| SCHEMBL9305228 | 0.79 | TDP1 (0.49) | TDP1HSP90AA1ESR2CHEK2SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768761-B | Novel benzimidazole derivatives | 卡尔那生物科学株式会社 | 2025-02-25 | — | — | CN | disclosed |
| CN-115768761-A | Novel benzimidazole derivatives | 卡尔那生物科学株式会社 | 2023-03-07 | — | — | CN | disclosed |