Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28922117 | 0.88 | ALDH1A1 (0.43) | ELANEALDH1A1CYP19A1LMNASMN1; SMN2 | |
| SCHEMBL28922133 | 0.88 | ELANE (0.38) | ELANEPOLBTP53ALDH1A1CYP19A1 | |
| SCHEMBL28922113 | 0.88 | MEN1 (0.45) | ELANEPOLBALDH1A1HTTL3MBTL1 | |
| SCHEMBL30168030 | 0.80 | MAPT (0.43) | TP53ALDH1A1HTTSMN1; SMN2HPGD | |
| SCHEMBL28922137 | 0.77 | CYP19A1 (0.40) | ELANEPOLBALDH1A1CYP19A1LMNA | |
| SCHEMBL28922114 | 0.76 | CYP19A1 (0.40) | ELANEALDH1A1CYP19A1SMN1; SMN2 | |
| SCHEMBL28922120 | 0.75 | CNR1 (0.45) | CYP19A1GAAMEN1MAPTKMT2A | |
| SCHEMBL30168036 | 0.74 | ALDH1A1 (0.40) | ALDH1A1LMNASMN1; SMN2GAAMEN1 | |
| SCHEMBL11076987 | 0.70 | CYP19A1 (0.72) | ALDH1A1CYP19A1SMN1; SMN2KDM4E | |
| SCHEMBL19707377 | 0.63 | ELANE (0.53) | ELANEPOLBTP53ALDH1A1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536573-B | Method for synthesizing azabicyclo [3.1.0] hexane-2-ketone compound | 河南师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115536573-A | Method for synthesizing azabicyclo [3.1.0] hexane-2-ketone compound | 河南师范大学 | 2022-12-30 | — | — | CN | disclosed |