Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28922113 | 0.87 | MEN1 (0.45) | MAPTALDH1A1MGLLKDM4ESCN9A | |
| SCHEMBL30168029 | 0.84 | MAPT (0.50) | MAPTALDH1A1MGLLSMN1; SMN2KMT2A | |
| SCHEMBL28922117 | 0.83 | ALDH1A1 (0.43) | MAPTCASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL30168035 | 0.80 | ELANE (0.42) | MAPTHSD17B10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28922133 | 0.76 | ELANE (0.38) | MAPTALDH1A1SMN1; SMN2TP53KMT2A | |
| SCHEMBL30168036 | 0.75 | ALDH1A1 (0.40) | MAPTCASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL28922114 | 0.74 | CYP19A1 (0.40) | ALDH1A1SMN1; SMN2SCN9A | |
| SCHEMBL28922137 | 0.74 | CYP19A1 (0.40) | HSD17B10ALDH1A1MGLLSMN1; SMN2KDM4E | |
| SCHEMBL28922120 | 0.71 | CNR1 (0.45) | MAPTKMT2AMEN1 | |
| SCHEMBL11079440 | 0.66 | CYP19A1 (0.55) | MAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536573-B | Method for synthesizing azabicyclo [3.1.0] hexane-2-ketone compound | 河南师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115536573-A | Method for synthesizing azabicyclo [3.1.0] hexane-2-ketone compound | 河南师范大学 | 2022-12-30 | — | — | CN | disclosed |