Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28842851 | 0.76 | MEN1 (0.37) | MEN1KMT2AALDH1A1ALKBH5FTO | |
| SCHEMBL30168076 | 0.76 | HTR2A (0.37) | MEN1KMT2ACYP2A6CYP1A2TDP1 | |
| SCHEMBL30168080 | 0.76 | MAOB (0.44) | MEN1KMT2ACYP2A6CYP1A2TDP1 | |
| SCHEMBL29600322 | 0.76 | HTR2A (0.37) | ALDH1A1ALKBH5FTOCYP2A6CYP1A2 | |
| SCHEMBL5662790 | 0.72 | NOTUM (0.41) | MEN1KMT2AALDH1A1ALKBH5FTO | |
| SCHEMBL16523549 | 0.68 | — | — | |
| SCHEMBL5604900 | 0.66 | BIRC5 (0.47) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL29896751 | 0.66 | BIRC5 (0.47) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL16506110 | 0.66 | XIAP (0.37) | ADRA2AADRA2BADRA2CXIAPBIRC2 | |
| SCHEMBL28423387 | 0.66 | RPS6KA5 (0.41) | MEN1KMT2AALDH1A1ALKBH5FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536662-A | Guanyl structure-containing tetracyclic indole compound, and synthesis method and application thereof | 广州大学 | 2022-12-30 | — | — | CN | disclosed |