Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168076 | 0.88 | HTR2A (0.37) | MAOBHSP90AA1ROCK1MAPTRXFP1 | |
| SCHEMBL30168073 | 0.84 | KCNH2 (0.38) | HSP90AA1ROCK1MAPTHTR2AHTR2C | |
| SCHEMBL29599854 | 0.84 | BIRC5 (0.41) | HSP90AA1ROCK1MAPTHTR2AHTR2C | |
| SCHEMBL6840186 | 0.79 | RXRA (0.48) | HSP90AA1ROCK1LMNAFGFR1RXRA | |
| SCHEMBL28894029 | 0.78 | MAOB (0.46) | MAOBHSP90AA1ROCK1MAPTRXFP1 | |
| SCHEMBL31454914 | 0.78 | ROCK1 (0.51) | MAOBHSP90AA1ROCK1MAPTRXFP1 | |
| SCHEMBL30168069 | 0.76 | MEN1 (0.35) | CYP2A6TDP1MEN1KMT2ACYP1A2 | |
| SCHEMBL28037181 | 0.75 | MAOB (0.43) | MAOBHSP90AA1ROCK1MAPTRXFP1 | |
| SCHEMBL17067770 | 0.74 | FGFR1 (0.51) | MAOBHSP90AA1ROCK1MAPTRXFP1 | |
| SCHEMBL9429195 | 0.74 | FABP4 (0.57) | MAOBHSP90AA1ROCK1MAPTFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536662-A | Guanyl structure-containing tetracyclic indole compound, and synthesis method and application thereof | 广州大学 | 2022-12-30 | — | — | CN | disclosed |