Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168080 | 0.88 | MAOB (0.44) | HTR2AHTR2CCYP2A6TDP1HSP90AA1 | |
| SCHEMBL28893986 | 0.78 | HTR2A (0.39) | HTR2AHTR2CCYP2A6DOT1LTDP1 | |
| SCHEMBL30168069 | 0.76 | MEN1 (0.35) | CYP2A6TDP1P2RX7CYP1A2MEN1 | |
| SCHEMBL30168073 | 0.75 | KCNH2 (0.38) | HTR2AHTR2CCYP2A6HSP90AA1P2RX7 | |
| SCHEMBL29599854 | 0.75 | BIRC5 (0.41) | HTR2AHTR2CCYP2A6HSP90AA1PRMT5 | |
| SCHEMBL5661673 | 0.74 | FGFR1 (0.47) | HTR2AHTR2CCYP2A6TDP1MAOB | |
| SCHEMBL29600322 | 0.73 | HTR2A (0.37) | HTR2AHTR2CCYP2A6P2RX7PRMT5 | |
| SCHEMBL22649105 | 0.71 | TP53 (0.46) | CYP2A6TDP1HSP90AA1MAOBMAPT | |
| SCHEMBL6840186 | 0.71 | RXRA (0.48) | HSP90AA1ROCK1RAPGEF4 | |
| SCHEMBL13183604 | 0.70 | HTR2A (0.45) | HTR2AHTR2CCYP2A6TDP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536662-A | Guanyl structure-containing tetracyclic indole compound, and synthesis method and application thereof | 广州大学 | 2022-12-30 | — | — | CN | disclosed |