Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | CASP6 | P55212 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24105032 | 1.00 | TDP1 (0.55) | TDP1CASP6POLBAPEX1CTDSP1 | |
| SCHEMBL85584 | 0.96 | TDP1 (0.53) | TDP1CASP6POLBAPEX1CTDSP1 | |
| SCHEMBL5415229 | 0.94 | TDP1 (0.52) | TDP1CASP6POLBAPEX1CTDSP1 | |
| SCHEMBL17979815 | 0.89 | TDP1 (0.51) | TDP1CASP6POLBAPEX1CTDSP1 | |
| SCHEMBL3675118 | 0.84 | ALDH1A1 (0.48) | TDP1CASP6POLBAPEX1CTDSP1 | |
| SCHEMBL8325167 | 0.83 | CASP6 (0.55) | TDP1CASP6POLBAPEX1CTDSP1 | |
| SCHEMBL85570 | 0.83 | POLB (0.55) | TDP1CASP6POLBAPEX1CTDSP1 | |
| SCHEMBL78723 | 0.83 | ALDH1A1 (0.62) | TDP1CASP6POLBAPEX1CTDSP1 | |
| SCHEMBL6140258 | 0.82 | TDP1 (0.69) | TDP1CASP6POLBAPEX1CTDSP1 | |
| SCHEMBL8338200 | 0.82 | AKR1C3 (0.46) | TDP1CASP6POLBAPEX1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025042408-A1 | METHODS OF TREATING CANCER | SCHRÖDINGER, INC. (US) | 2025-02-27 | — | — | WO | disclosed |
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |