Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30371499 | 0.88 | SMN1; SMN2 (0.47) | MEN1KMT2APKML3MBTL1ALDH1A1 | |
| SCHEMBL4244000 | 0.79 | L3MBTL1 (0.64) | MEN1KMT2APKML3MBTL1ABL1 | |
| SCHEMBL15010830 | 0.74 | TSHR (0.62) | MEN1KMT2APKML3MBTL1KDM4E | |
| SCHEMBL5307150 | 0.73 | ALDH1A1 (0.57) | L3MBTL1ALDH1A1LMNAMAPTGAA | |
| SCHEMBL2963400 | 0.72 | ABL1 (0.52) | TRPV4MEN1KMT2APKML3MBTL1 | |
| SCHEMBL30228776 | 0.68 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL15218459 | 0.68 | KDM1A (0.40) | KDM4EALDH1A1TDP1 | |
| SCHEMBL20489103 | 0.68 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL3407131 | 0.68 | L3MBTL1 (0.64) | KMT2AL3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL24512344 | 0.68 | ALDH1A1 (0.58) | MEN1KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |