Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168479 | 0.82 | KCNQ3 (0.40) | KMT2AMEN1ALDH1A1GAAKDM4E | |
| SCHEMBL31087263 | 0.76 | KDR (0.53) | KMT2AMEN1ALDH1A1GAAMAPT | |
| SCHEMBL30168480 | 0.75 | ALOX15 (0.38) | KMT2AMEN1ALDH1A1GAALMNA | |
| SCHEMBL29643927 | 0.70 | POLB (0.49) | KMT2AMEN1ALDH1A1GAACA2 | |
| SCHEMBL28615124 | 0.70 | POLB (0.49) | KMT2AMEN1ALDH1A1GAACA2 | |
| SCHEMBL239212 | 0.69 | KDM4E (0.45) | ALDH1A1GAAMAPTKDM4ELMNA | |
| SCHEMBL16088601 | 0.69 | KMT2A (0.51) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL20599378 | 0.69 | PDE4A (0.38) | KMT2AMEN1ALDH1A1GAAKDM4E | |
| SCHEMBL25009031 | 0.68 | SOS2 (0.37) | KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL25010840 | 0.68 | MEN1 (0.42) | KMT2AMEN1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380928-A1 | PPARG INVERSE AGONISTS AND USES THEREOF | Flare Therapeutics Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| WO-2023014861-A1 | PPARG INVERSE AGONISTS AND USES THEREOF | FLARE THERAPEUTICS INC. (US) | 2023-02-09 | — | — | WO | disclosed |