Sugi Predict

Sugi Predict / Compounds / SCHEMBL30168549

SCHEMBL30168549

SCHEMBL30168549

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)NC(=O)[C@@H]2CCCN2)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ EPRS1 P07814 2/20 1.00
▸ SARS1 P49591 1/20 0.67
▸ TARS1 P26639 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30619433 1.00 EPRS1 (1.00) EPRS1SARS1TARS1
SCHEMBL117454 1.00 EPRS1 (1.00) EPRS1SARS1TARS1
SCHEMBL13773222 0.89 EPRS1 (0.79) EPRS1SARS1TARS1
SCHEMBL13773215 0.89 EPRS1 (0.79) EPRS1SARS1TARS1
SCHEMBL18314782 0.86 EPRS1 (0.76) EPRS1
SCHEMBL31533324 0.86 EPRS1 (0.76) EPRS1
SCHEMBL13773216 0.84 TARS1 (0.78) SARS1TARS1
SCHEMBL5666889 0.83 SARS1 (0.75) SARS1TARS1
SCHEMBL29765425 0.83 SARS1 (0.75) SARS1TARS1
SCHEMBL6709589 0.83 SARS1 (0.75) SARS1TARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115997022-A Completely orthogonal system for protein synthesis in bacterial cells 西北大学 2023-04-21 — — CN disclosed
US-20230117150-A1 FULLY ORTHOGONAL SYSTEM FOR PROTEIN SYNTHISIS IN BACTERIAL CELLS NATIONAL SCIENCE FOUNDATION 2023-04-20 — — US disclosed
EP-4127183-A2 FULLY ORTHOGONAL SYSTEM FOR PROTEIN SYNTHESIS IN BACTERIAL CELLS Northwestern University (US) 2023-02-08 — — EP disclosed
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