Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SARS1 | P49591 | 1/20 | 0.75 |
| ▸ | TARS1 | P26639 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5666889 | 1.00 | SARS1 (0.75) | SARS1TARS1 | |
| SCHEMBL29765425 | 1.00 | SARS1 (0.75) | SARS1TARS1 | |
| SCHEMBL14178246 | 0.94 | TARS1 (0.76) | SARS1TARS1 | |
| SCHEMBL13773216 | 0.90 | TARS1 (0.78) | SARS1TARS1 | |
| Alasa SCHEMBL29531843 | 0.87 | TARS1 (0.87) | SARS1TARS1 | |
| Alasa SCHEMBL4320823 | 0.87 | TARS1 (0.87) | SARS1TARS1 | |
| Alasa SCHEMBL21067643 | 0.87 | TARS1 (0.87) | SARS1TARS1 | |
| SCHEMBL178863 | 0.87 | — | — | |
| SCHEMBL13773222 | 0.86 | EPRS1 (0.79) | SARS1TARS1 | |
| SCHEMBL21067959 | 0.86 | SARS1 (1.00) | SARS1TARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040224981-A1 | Antibacterial methods and compositions | REPLIDYNE, INC. | 2004-11-11 | — | — | US | disclosed |
| US-6197495-B1 | IDENTIFYING ENZYME INHIBITORS BY USING COMPUTER PROGRAM TO CREATE THREE DIMENSIONAL STRUCTURE OF ENZYME ACTIVE SITE AND OF TEST COMPOUND, DISPLAYING AND SUPERIMPOSING THE IMAGES, THEN TESTING COMPOUND IN BIOLOGICAL SYNTHETASE ASSAY | SMITHKLINE BEECHAM CORPORATION | 2001-03-06 | — | — | US | disclosed |
| US-6037117-A | DESIGNING DRUGS BY USING THE STRUCTURAL COORDINATES OF BACTERIAL ENZYME PROTEIN CRYSTALS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224981-A1 | Antibacterial methods and compositions | AARS1, NOP2, NSUN3 | SARS1 15/4885TARS1 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.