SCHEMBL30168693

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	F2	P00734	4/20	0.56

▸	KEAP1	Q14145	2/20	0.56

▸	GLP1R	P43220	10/20	0.55

▸	KDM1A	O60341	1/20	0.53

▸	NPY1R	P25929	2/20	0.52

▸	NPY2R	P49146	2/20	0.52

▸	NPY4R	P50391	2/20	0.52

▸	NPY5R	Q15761	2/20	0.52

▸	SCTR	P47872	1/20	0.52

▸	BECN1	Q14457	1/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30168734	1.00	F2 (0.56)	F2KEAP1GLP1RKDM1ANPY1R
SCHEMBL30168770	0.99	F2 (0.58)	F2KEAP1GLP1RKDM1ANPY1R
SCHEMBL29836365	0.97	F2 (0.55)	F2KEAP1GLP1RKDM1ASCTR
SCHEMBL29836528	0.97	F2 (0.55)	F2KEAP1GLP1RKDM1ASCTR
SCHEMBL30168691	0.97	KEAP1 (0.56)	F2KEAP1GLP1RKDM1ANPY1R
SCHEMBL29836324	0.96	F2 (0.57)	F2KEAP1GLP1RKDM1ASCTR
SCHEMBL30168702	0.96	MAPK8 (0.56)	F2KEAP1GLP1RKDM1ABECN1
SCHEMBL30168757	0.96	KEAP1 (0.55)	F2KEAP1GLP1RNPY1RNPY2R
SCHEMBL30168694	0.95	KEAP1 (0.59)	F2KEAP1GLP1RKDM1ANPY1R
SCHEMBL30168767	0.95	KEAP1 (0.59)	F2KEAP1GLP1RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12428638-B2	Three-component CRISPR/Cas complex system and uses thereof	THE JACKSON LABORATORY (US)	2025-09-30	—	—	US	disclosed
US-20230071712-A1	THREE-COMPONENT CRISPR/CAS COMPLEX SYSTEM AND USES THEREOF	THE JACKSON LABORATORY (US)	2023-03-09	—	—	US	disclosed