SCHEMBL30168694

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	KEAP1	Q14145	1/20	0.59

▸	F2	P00734	4/20	0.58

▸	GLP1R	P43220	3/20	0.54

▸	MAPK8	P45983	1/20	0.54

▸	MAPK9	P45984	1/20	0.54

▸	MAPK10	P53779	1/20	0.54

▸	KDM1A	O60341	3/20	0.54

▸	NPY2R	P49146	5/20	0.53

▸	NPY4R	P50391	5/20	0.53

▸	NPY5R	Q15761	5/20	0.53

▸	NPY1R	P25929	4/20	0.53

▸	BECN1	Q14457	1/20	0.53

▸	MAOB	P27338	1/20	0.52

▸	KDM5A	P29375	1/20	0.52

▸	KDM1B	Q8NB78	1/20	0.52

▸	TFPI	P10646	1/20	0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29836301	0.97	KEAP1 (0.57)	KEAP1F2GLP1RMAPK8MAPK9
SCHEMBL30168770	0.97	F2 (0.58)	KEAP1F2GLP1RKDM1ANPY2R
SCHEMBL30168706	0.96	KEAP1 (0.57)	KEAP1F2GLP1RMAPK8MAPK9
SCHEMBL30168691	0.96	KEAP1 (0.56)	KEAP1F2GLP1RMAPK8MAPK9
SCHEMBL29836297	0.95	KEAP1 (0.57)	KEAP1F2GLP1RMAPK8MAPK9
SCHEMBL30168734	0.95	F2 (0.56)	KEAP1F2GLP1RKDM1ANPY2R
SCHEMBL30168693	0.95	F2 (0.56)	KEAP1F2GLP1RKDM1ANPY2R
SCHEMBL30168702	0.95	MAPK8 (0.56)	KEAP1F2GLP1RMAPK8MAPK9
SCHEMBL30168757	0.95	KEAP1 (0.55)	KEAP1F2GLP1RMAPK8MAPK9
SCHEMBL30168767	0.94	KEAP1 (0.59)	KEAP1F2GLP1RMAPK8MAPK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-12428638-B2	Three-component CRISPR/Cas complex system and uses thereof	THE JACKSON LABORATORY (US)	2025-09-30	—	—	US	disclosed
US-20230071712-A1	THREE-COMPONENT CRISPR/CAS COMPLEX SYSTEM AND USES THEREOF	THE JACKSON LABORATORY (US)	2023-03-09	—	—	US	disclosed