Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032565 | 1.00 | MEN1 (0.34) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL31570546 | 0.86 | MEN1 (0.35) | MEN1USP2KMT2AKEAP1NFE2L2 | |
| SCHEMBL30056973 | 0.78 | MAPK14 (0.32) | MAPK14PDE3BPDE3A | |
| SCHEMBL29516860 | 0.76 | S100A4 (0.37) | KMT2AMAPK14 | |
| SCHEMBL25529496 | 0.76 | S100A4 (0.37) | KMT2AMAPK14 | |
| SCHEMBL20764947 | 0.72 | TDP1 (0.38) | MEN1KMT2AMAPK14PDE3BPDE3A | |
| SCHEMBL30439702 | 0.72 | TDP1 (0.38) | MEN1KMT2AMAPK14PDE3BPDE3A | |
| SCHEMBL26162649 | 0.71 | GRIN2D (0.37) | MAPK14PDE3BPDE3AIDH2 | |
| SCHEMBL31094848 | 0.70 | MAPT (0.57) | MEN1KMT2AMAPK14 | |
| SCHEMBL19175120 | 0.70 | AR (0.46) | MAPK14PDE3BPDE3AIDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655690-B | Pyrazolopyridinone compounds | 詹森药业有限公司 | 2023-01-10 | — | — | CN | disclosed |