Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LGMN | Q99538 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21000994 | 1.00 | MAPT (0.45) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL30168906 | 0.79 | MAPT (0.50) | MAPTGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL21032115 | 0.79 | MAPT (0.50) | MAPTGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24196356 | 0.79 | SMN1; SMN2 (0.49) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL2062687 | 0.79 | GAA (0.45) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL518889 | 0.76 | ALDH1A1 (0.50) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL2376896 | 0.76 | LGMN (0.49) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL22684291 | 0.75 | LGMN (0.53) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL29744988 | 0.74 | LGMN (0.51) | MAPTGAASMN1; SMN2LGMNALDH1A1 | |
| SCHEMBL19212240 | 0.74 | SMN1; SMN2 (0.46) | MAPTGAASMN1; SMN2LGMNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655690-B | Pyrazolopyridinone compounds | 詹森药业有限公司 | 2023-01-10 | — | — | CN | disclosed |