Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21001112 | 1.00 | KDM4E (0.53) | KDM4EGAAALDH1A1HTTMAPT | |
| SCHEMBL25796769 | 0.85 | HTT (0.49) | KDM4EGAAALDH1A1HTTMAPT | |
| SCHEMBL939398 | 0.81 | ALDH1A1 (0.68) | GAAALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL23360731 | 0.81 | KDM4E (0.46) | KDM4EGAAALDH1A1HTTMAPT | |
| SCHEMBL21031716 | 0.80 | ALDH1A1 (0.67) | KDM4EGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL21001001 | 0.80 | HSD17B10 (0.43) | KDM4EGAAALDH1A1HTTHPGD | |
| SCHEMBL29648280 | 0.80 | HSD17B10 (0.43) | KDM4EGAAALDH1A1HTTHPGD | |
| SCHEMBL23360736 | 0.79 | ALDH1A1 (0.44) | KDM4EGAAALDH1A1HTTMAPT | |
| SCHEMBL23168572 | 0.79 | HSD17B10 (0.42) | KDM4EGAAALDH1A1HTTL3MBTL1 | |
| SCHEMBL21001153 | 0.74 | ALDH1A1 (0.40) | KDM4EGAAALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655690-B | Pyrazolopyridinone compounds | 詹森药业有限公司 | 2023-01-10 | — | — | CN | disclosed |