Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 10/20 | 0.61 |
| ▸ | ARG2 | P78540 | 9/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894168 | 1.00 | ARG1 (0.61) | ARG1ARG2DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL894877 | 0.99 | ARG1 (0.60) | ARG1ARG2DRD2HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL894268 | 0.98 | ARG1 (0.59) | ARG1ARG2DRD2HTR1AHTR2A | |
| SCHEMBL20683338 | 0.86 | DRD2 (0.54) | DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL895007 | 0.83 | ARG1 (0.71) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894875 | 0.82 | ARG1 (0.69) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894979 | 0.81 | ARG1 (0.68) | ARG1ARG2 | |
| SCHEMBL895199 | 0.78 | ARG1 (0.72) | ARG1ARG2 | |
| SCHEMBL895065 | 0.77 | ARG1 (0.80) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894954 | 0.77 | ARG1 (0.70) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283332-A1 | USES OF ARGINASE INHIBITORS FOR MANAGING KIDNEY DISEASE AND CARDIOVASCULAR CONDITIONS | EMORY UNIVERSITY (US) | 2023-01-12 | — | — | WO | disclosed |