SCHEMBL30169940

SCHEMBL30169940

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nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.47
ACE P12821 1/20 0.47
CPA1 P15085 1/20 0.47
ACE2 Q9BYF1 1/20 0.47
TERT O14746 1/20 0.42
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
PTGS2 P35354 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ECE1 P42892 1/20 0.38
CTSD P07339 2/20 0.34
ENPEP Q07075 7/20 0.33
PTGS1 P23219 1/20 0.33
GSTK1 Q9Y2Q3 1/20 0.33
MMP2 P08253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051565 0.94 MME (0.51) MMEACECPA1ACE2TERT
SCHEMBL30051352 0.87 MME (0.53) MMEACECPA1ACE2TERT
SCHEMBL30052810 0.87 MME (0.56) MMEACECPA1ACE2TERT
SCHEMBL10862344 0.84 CTSD (0.42) CTSD
SCHEMBL10862333 0.84 CTSD (0.42) CTSD
SCHEMBL30668294 0.84 MME (0.44) MMEACECPA1ACE2ENPEP
SCHEMBL31420017 0.84 ENPEP (0.47) TERTCTSDENPEP
SCHEMBL29448566 0.83 MME (0.43) MMEACECPA1ACE2TERT
SCHEMBL30051375 0.83 MME (0.51) MMEACECPA1ACE2ALDH1A1
SCHEMBL29608926 0.83 MME (0.46) MMEACECPA1ACE2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111778267-B Plutella xylostella Trypsin-9 gene and application thereof 华南农业大学 2023-02-03 CN disclosed