SCHEMBL30169941

SCHEMBL30169941

NC(CCCCB(O)O)(C(=O)O)C1CCN(CCCc2ccc(F)cc2F)CC1

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 20/20 0.71
ARG2 P78540 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL894204 1.00 ARG1 (0.71) ARG1ARG2
Hydrochloric Acid SCHEMBL895812 0.99 ARG1 (0.70) ARG1ARG2
SCHEMBL20156683 0.90 ARG1 (0.57) ARG1ARG2
SCHEMBL895249 0.83 ARG1 (1.00) ARG1ARG2
SCHEMBL30169937 0.83 ARG1 (1.00) ARG1ARG2
Hydrochloric Acid SCHEMBL894665 0.83 ARG1 (0.98) ARG1ARG2
SCHEMBL20485919 0.82 ARG1 (0.72) ARG1ARG2
SCHEMBL894654 0.81 ARG1 (0.80) ARG1ARG2
SCHEMBL894939 0.81 ARG1 (0.68) ARG1ARG2
SCHEMBL30169823 0.81 ARG1 (0.68) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023283332-A1 USES OF ARGINASE INHIBITORS FOR MANAGING KIDNEY DISEASE AND CARDIOVASCULAR CONDITIONS EMORY UNIVERSITY (US) 2023-01-12 WO disclosed