Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 17/20 | 0.79 |
| ▸ | ARG2 | P78540 | 17/20 | 0.79 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894745 | 1.00 | ARG1 (0.79) | ARG1ARG2SIGMAR1MCHR1 | |
| Hydrochloric Acid SCHEMBL894841 | 0.99 | ARG1 (0.78) | ARG1ARG2SIGMAR1MCHR1 | |
| SCHEMBL895255 | 0.89 | ARG1 (1.00) | ARG1ARG2 | |
| SCHEMBL12292595 | 0.89 | ARG1 (1.00) | ARG1ARG2 | |
| SCHEMBL895258 | 0.89 | ARG1 (1.00) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL895558 | 0.88 | ARG1 (0.98) | ARG1ARG2 | |
| SCHEMBL894278 | 0.85 | ARG1 (0.78) | ARG1ARG2SIGMAR1 | |
| SCHEMBL19575883 | 0.85 | ARG1 (1.00) | ARG1ARG2SIGMAR1 | |
| SCHEMBL895916 | 0.85 | ARG1 (1.00) | ARG1ARG2SIGMAR1 | |
| SCHEMBL30772139 | 0.85 | ARG1 (1.00) | ARG1ARG2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283332-A1 | USES OF ARGINASE INHIBITORS FOR MANAGING KIDNEY DISEASE AND CARDIOVASCULAR CONDITIONS | EMORY UNIVERSITY (US) | 2023-01-12 | — | — | WO | disclosed |