Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 17/20 | 0.67 |
| ▸ | ARG2 | P78540 | 17/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL894063 | 1.00 | ARG1 (0.67) | ARG1ARG2MEN1KMT2ANPY2R | |
| SCHEMBL20683428 | 0.90 | ARG1 (0.53) | ARG1ARG2MEN1KMT2ANPY2R | |
| SCHEMBL19055915 | 0.89 | ARG1 (0.64) | ARG1ARG2 | |
| SCHEMBL895476 | 0.88 | ARG1 (0.82) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL895207 | 0.87 | ARG1 (0.80) | ARG1ARG2 | |
| SCHEMBL30169925 | 0.83 | ARG1 (0.80) | ARG1ARG2MEN1KMT2A | |
| SCHEMBL895490 | 0.83 | ARG1 (0.80) | ARG1ARG2MEN1KMT2A | |
| SCHEMBL894747 | 0.83 | ARG1 (0.76) | ARG1ARG2 | |
| SCHEMBL10266057 | 0.83 | ARG1 (0.76) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894649 | 0.82 | ARG1 (0.75) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283332-A1 | USES OF ARGINASE INHIBITORS FOR MANAGING KIDNEY DISEASE AND CARDIOVASCULAR CONDITIONS | EMORY UNIVERSITY (US) | 2023-01-12 | — | — | WO | disclosed |