Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38655692 | 0.85 | GAA (0.51) | KDM4EHTTALDH1A1GFERCNR1 | |
| SCHEMBL38655682 | 0.85 | GAA (0.51) | KDM4EHTTALDH1A1GFERCNR1 | |
| SCHEMBL38656647 | 0.85 | GAA (0.51) | KDM4EHTTALDH1A1GFERCNR1 | |
| SCHEMBL30170028 | 0.83 | GAA (0.46) | KDM4EHTTALDH1A1GFERCNR1 | |
| SCHEMBL26460421 | 0.83 | ALDH1A1 (0.54) | KDM4EHTTALDH1A1GFERLMNA | |
| SCHEMBL8581974 | 0.80 | KDM4E (0.55) | KDM4EHTTALDH1A1GFERLMNA | |
| SCHEMBL8581979 | 0.80 | KDM4E (0.55) | KDM4EHTTALDH1A1GFERLMNA | |
| SCHEMBL8580257 | 0.80 | KDM4C (0.66) | KDM4EHTTALDH1A1GFERLMNA | |
| SCHEMBL8580260 | 0.80 | KDM4C (0.66) | KDM4EHTTALDH1A1GFERLMNA | |
| SCHEMBL30170152 | 0.79 | LONP1 (0.59) | KDM4EHTTALDH1A1CNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4366831-A1 | ANTI-VIRAL COMPOUNDS | Aligos Therapeutics, Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023283256-A1 | ANTI-VIRAL COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2023-01-12 | — | — | WO | disclosed |