SCHEMBL38656647

SCHEMBL38656647

COC(=O)[C@H](NC(=O)c1ccccn1)C(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.51
SMN1; SMN2 Q16637 5/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
PKM P14618 2/20 0.49
MAPT P10636 1/20 0.49
GFER P55789 1/20 0.48
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 2/20 0.48
HTT P42858 2/20 0.48
CNR1 P21554 5/20 0.47
CNR2 P34972 5/20 0.47
HPGD P15428 1/20 0.47
CDK5 Q00535 1/20 0.47
PAX8 Q06710 1/20 0.47
CDK5R1 Q15078 1/20 0.47
LMNA P02545 1/20 0.46
GRM4 Q14833 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38655692 1.00 GAA (0.51) GAASMN1; SMN2NPC1RAB9APKM
SCHEMBL38655682 1.00 GAA (0.51) GAASMN1; SMN2NPC1RAB9APKM
SCHEMBL30170028 0.89 GAA (0.46) GAASMN1; SMN2NPC1RAB9APKM
SCHEMBL30170478 0.85 KDM4E (0.50) GAASMN1; SMN2NPC1RAB9APKM
SCHEMBL4987029 0.82 SMN1; SMN2 (0.54) GAASMN1; SMN2NPC1RAB9APKM
SCHEMBL15549120 0.81 KDM4E (0.52) GAASMN1; SMN2NPC1RAB9APKM
SCHEMBL15549121 0.81 KDM4E (0.52) GAASMN1; SMN2NPC1RAB9APKM
SCHEMBL28674012 0.81 KDM4E (0.55) GAASMN1; SMN2NPC1RAB9APKM
SCHEMBL26460421 0.80 ALDH1A1 (0.54) GAASMN1; SMN2NPC1RAB9APKM
SCHEMBL1106971 0.78 KDM4E (0.63) GAASMN1; SMN2NPC1RAB9APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use GIPR, MC2R, GRPR GAA 633/4885SMN1; SMN2 881/4885NPC1 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.