Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.67 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759475 | 1.00 | CRBN (0.67) | CRBNCSNK1A1MAP1LC3B | |
| SCHEMBL30170881 | 0.93 | CRBN (0.65) | CRBNCSNK1A1MAP1LC3B | |
| SCHEMBL21759818 | 0.93 | CRBN (0.65) | CRBNCSNK1A1MAP1LC3B | |
| SCHEMBL21759952 | 0.85 | CRBN (0.71) | CRBN | |
| SCHEMBL24046504 | 0.85 | CRBN (0.67) | CRBN | |
| SCHEMBL21759455 | 0.85 | CRBN (0.67) | CRBN | |
| SCHEMBL30128254 | 0.85 | CRBN (0.67) | CRBN | |
| SCHEMBL21855163 | 0.83 | CRBN (0.65) | CRBN | |
| SCHEMBL23535151 | 0.83 | CRBN (0.70) | CRBN | |
| SCHEMBL21760436 | 0.83 | CRBN (0.70) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110772-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | Cullgen (Shanghai), Inc. (CN) | 2023-01-04 | — | — | EP | disclosed |