Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28948269 | 0.86 | KCNK3 (0.44) | MAPTKDM4ETP53SMN1; SMN2NPBWR1 | |
| SCHEMBL2488918 | 0.82 | MAPT (0.51) | MAPTKDM1AKDM4EP2RX3ESR2 | |
| SCHEMBL2076226 | 0.81 | OPRD1 (0.46) | MAPTESR2HPGDSTP53LMNA | |
| SCHEMBL17328049 | 0.80 | HPGDS (0.47) | MAPTKDM1AESR2HPGDSNR1H2 | |
| SCHEMBL30171269 | 0.80 | ESR2 (0.48) | MAPTKDM4EESR2HPGDSNR1H2 | |
| SCHEMBL20792551 | 0.80 | MAPT (0.53) | MAPTESR2HPGDSNR1H2HDAC1 | |
| SCHEMBL17868597 | 0.80 | KCNK3 (0.48) | MAPTKDM1AKDM4EP2RX3ESR2 | |
| SCHEMBL4152639 | 0.80 | KDM1A (0.43) | MAPTKDM1AP2RX3TP53LMNA | |
| SCHEMBL30915383 | 0.80 | MAPT (0.54) | MAPTKDM1AKDM4EP2RX3ESR2 | |
| SCHEMBL7986367 | 0.79 | ESR2 (0.47) | MAPTESR2HPGDSNR1H2SLC34A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4626888-A1 | COMPOUNDS | Redx Pharma Limited (GB) | 2025-10-08 | — | — | EP | disclosed |
| WO-2024115890-A1 | COMPOUNDS | REDX PHARMA PLC (GB) | 2024-06-06 | — | — | WO | disclosed |
| CN-115677729-A | AAK1 inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-02-03 | — | — | CN | disclosed |