SCHEMBL30172191

SCHEMBL30172191

C[C@](O)(CNC1CCN(Cc2ccc(Cl)cc2)CC1)COc1ccccc1CCO

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ABCB11 O95342 2/20 0.69
CCR1 P32246 1/20 0.59
BCHE P06276 5/20 0.47
ACHE P22303 5/20 0.47
BACE1 P56817 5/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
SSTR1 P30872 1/20 0.45
SSTR4 P31391 1/20 0.45
POLB P06746 1/20 0.45
CCR5 P51681 2/20 0.43
DRD4 P21917 1/20 0.42
SIGMAR1 Q99720 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HTR1A P08908 1/20 0.41
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1682973 1.00 ABCB11 (0.69) ABCB11CCR1BCHEACHEBACE1
Trifluoroacetic Acid SCHEMBL1950534 0.93 ABCB11 (0.66) ABCB11CCR1BCHEACHEBACE1
SCHEMBL3145745 0.89 ABCB11 (0.70) ABCB11CCR1BCHEACHEBACE1
SCHEMBL4712843 0.89 ABCB11 (0.69) ABCB11CCR1BCHEACHEBACE1
SCHEMBL3144689 0.89 ABCB11 (0.69) ABCB11CCR1BCHEACHEBACE1
SCHEMBL3135586 0.87 ABCB11 (0.67) ABCB11CCR1BCHEACHEBACE1
SCHEMBL3135724 0.87 ABCB11 (0.72) ABCB11CCR1BCHEACHEBACE1
Trifluoroacetic Acid SCHEMBL3141729 0.86 ABCB11 (0.66) ABCB11CCR1BCHEACHEBACE1
SCHEMBL1950533 0.84 ABCB11 (0.55) ABCB11CCR1BCHEACHEBACE1
Trifluoroacetic Acid SCHEMBL3149755 0.84 ABCB11 (0.67) ABCB11CCR1BCHEACHEBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4115885-A1 A PHARMACEUTICAL COMPOSITION COMPRISING BAY 86-5277 AND SALTS THEREOF FOR USE IN THE TREATMENT OF VIRAL INFECTIONS AND HYPERINFLAMMATION Charité - Universitätsmedizin Berlin (DE) 2023-01-11 EP disclosed