Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693309 | 1.00 | KMT2A (0.52) | KMT2APKMCHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL1623810 | 0.99 | KMT2A (0.51) | KMT2APKMCHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL1624112 | 0.99 | KMT2A (0.51) | KMT2APKMCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3274646 | 0.92 | USP30 (0.53) | KMT2APKMMEN1HDAC1HDAC6 | |
| SCHEMBL13738679 | 0.92 | USP30 (0.53) | KMT2APKMMEN1HDAC1HDAC6 | |
| SCHEMBL1624125 | 0.92 | USP30 (0.53) | KMT2APKMMEN1HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL3272901 | 0.90 | USP30 (0.52) | KMT2APKMMEN1HDAC1HDAC6 | |
| SCHEMBL2009587 | 0.82 | GBA1 (0.53) | KMT2APKMMEN1HDAC1HDAC6 | |
| SCHEMBL8773484 | 0.82 | HDAC1 (0.61) | KMT2APKMMEN1HDAC1HDAC6 | |
| SCHEMBL3372477 | 0.80 | HDAC1 (0.58) | KMT2APKMMEN1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184751-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | BALLELL-PAGES LLUIS | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184751-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | SDHA, SDHB, NNT | KMT2A 4235/4885PKM 1374/4885CHRNB2 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.