Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 1/20 | 0.49 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 4/20 | 0.48 |
| ▸ | AXL | P30530 | 2/20 | 0.48 |
| ▸ | MAP3K11 | Q16584 | 5/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602138 | 1.00 | CCNK (0.49) | CCNKCDK12PRKCIAXLMAP3K11 | |
| SCHEMBL28603791 | 0.83 | PRKCI (0.51) | CCNKCDK12PRKCIAXLMAP3K11 | |
| SCHEMBL30173290 | 0.83 | PRKCI (0.51) | CCNKCDK12PRKCIAXLMAP3K11 | |
| SCHEMBL30173298 | 0.79 | RPS6KA3 (0.49) | CCNKCDK12PRKCIAXLNUDT1 | |
| SCHEMBL28596894 | 0.79 | RPS6KA3 (0.49) | CCNKCDK12PRKCIAXLNUDT1 | |
| SCHEMBL28596854 | 0.78 | PRKCI (0.59) | CCNKCDK12PRKCIAXLNUDT1 | |
| SCHEMBL30173348 | 0.78 | PRKCI (0.59) | CCNKCDK12PRKCIAXLNUDT1 | |
| SCHEMBL28606321 | 0.77 | NUDT1 (0.68) | PRKCIAXLNUDT1DYRK1AJAK2 | |
| SCHEMBL28609163 | 0.77 | AXL (0.61) | CCNKCDK12PRKCIAXLNUDT1 | |
| SCHEMBL30173316 | 0.77 | AXL (0.61) | CCNKCDK12PRKCIAXLNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-B | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2023-01-03 | — | — | CN | disclosed |