Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 2/20 | 0.51 |
| ▸ | AXL | P30530 | 2/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | SGK1 | O00141 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603791 | 1.00 | PRKCI (0.51) | PRKCIAXLNUDT1DHFRCLK1 | |
| SCHEMBL28602138 | 0.83 | CCNK (0.49) | PRKCIAXLNUDT1MAP3K11CCNK | |
| SCHEMBL30173270 | 0.83 | CCNK (0.49) | PRKCIAXLNUDT1MAP3K11CCNK | |
| SCHEMBL30173305 | 0.82 | JAK2 (0.58) | PRKCIAXLNUDT1CDK8CCNK | |
| SCHEMBL3725709 | 0.82 | JAK2 (0.58) | PRKCIAXLNUDT1CDK8CCNK | |
| SCHEMBL28596878 | 0.82 | NUDT1 (0.51) | PRKCIAXLNUDT1MAP3K11CDK8 | |
| SCHEMBL28606321 | 0.80 | NUDT1 (0.68) | PRKCIAXLNUDT1DHFRCDK8 | |
| SCHEMBL30173337 | 0.80 | NUDT1 (0.68) | PRKCIAXLNUDT1DHFRCDK8 | |
| SCHEMBL30173298 | 0.79 | RPS6KA3 (0.49) | PRKCIAXLNUDT1CDK8CCNK | |
| SCHEMBL28596894 | 0.79 | RPS6KA3 (0.49) | PRKCIAXLNUDT1CDK8CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-B | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2023-01-03 | — | — | CN | disclosed |