Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 12/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603783 | 1.00 | KIT (0.48) | KITAXLPRKCIDYRK1AADORA2A | |
| SCHEMBL30173295 | 0.83 | BRD4 (0.66) | KITAXLPRKCIBRD4MAP3K11 | |
| SCHEMBL28598681 | 0.83 | BRD4 (0.66) | KITAXLPRKCIBRD4MAP3K11 | |
| SCHEMBL30173348 | 0.83 | PRKCI (0.59) | AXLPRKCIDYRK1AKMO | |
| SCHEMBL30173347 | 0.83 | PRKCI (0.59) | AXLPRKCIDYRK1AKMO | |
| SCHEMBL28596854 | 0.83 | PRKCI (0.59) | AXLPRKCIDYRK1AKMO | |
| SCHEMBL28596860 | 0.81 | AXL (0.53) | KITAXLPRKCIDYRK1AMAP3K11 | |
| SCHEMBL30173308 | 0.81 | AXL (0.53) | KITAXLPRKCIDYRK1AMAP3K11 | |
| SCHEMBL1079890 | 0.77 | AXL (0.62) | KITAXLPRKCIBRD4 | |
| SCHEMBL30731298 | 0.77 | AXL (0.62) | KITAXLPRKCIBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-B | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2023-01-03 | — | — | CN | disclosed |